Application of Amarogentin
The bitter taste of Amarogentin has led to its traditional use in herbal medicine and the beverage industry. In traditional medicine, Amarogentin-containing preparations are believed to have digestive and appetite-stimulating properties. It is also used in the formulation of various herbal remedies for supporting digestive health.
In the beverage industry, Amarogentin is responsible for the characteristic bitter taste of beverages made from Gentian, such as Gentian liqueur or bitters. These bitter beverages are often used as aperitifs, believed to stimulate the appetite before a meal.
Modern scientific research
Studies have shown that Amarogentin and other bitter compounds in Gentian may have various biological activities, including antioxidant, anti-inflammatory, and hepatoprotective properties.
Amarogentin has the effects of protecting the liver and gallbladder, inhibiting bacteria, and diuresis.
Amarogentin, an agonist of the bitter taste receptor TAS2R1, inhibits substanceP-induced production of newly synthesized TNF-α in LAD-2 cells.
Amarogentin induces apoptosis of human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signaling pathway.
Amarogentin (AG) can interact with the α2 subunit of AMP-activated protein kinase (AMPK) and activate trimer kinase.
Parameters of Amarogentina
|Brand||Natural Micron Pharm Tech|
|Melting point||229-230° (monohydrate)|
|Alpha||D20 -116.6° (methanol)|
|Solubility||DMF: 1 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.1 mg/ml|
|Place of Origin||China|
|Shelf Life||Under the transportation and storage conditions specified in this standard, the shelf life is two years from the date of production if the packaging is complete and unopened.|
|Package||The product is packed and sealed in drums or bags that do not affect the quality of the product.|
|Storage||2-8℃，protected from light,keep package airproofed when not in use.|