Product Name: Recombinant Human Epidermal Growth Factor (EGF)
Other Name: EGF; rhEGF
Recombinant Human Epidermal Growth Factor (EGF) Application:
Recombinant human epidermal growth factor (rhEGF) is an active protein identical to the body’s own epidermal growth factor, produced on a large scale through genetic engineering. It is primarily used to promote the growth, proliferation, and differentiation of epithelial cells in the skin, mucous membranes, and other tissues, thereby accelerating wound healing. It is widely applied in medical and skincare fields.
- What is EGF?
Epidermal Growth Factor (EGF): Initially discovered as a small polypeptide (protein) in the human body, it naturally exists within the body and is responsible for regulating cell growth, proliferation, and differentiation. In particular, when the skin is damaged, it accumulates in large quantities to direct cells in “repairing wounds.”.
“Recombinant” technology: “Recombinant” refers to the process where scientists insert the gene encoding human EGF into specific host cells (such as E. coli or yeast) using genetic engineering techniques. These microorganisms then function like “factories,” producing human-derived EGF in large quantities, with high efficiency and purity. This approach eliminates the difficulties, inefficiencies, and ethical concerns associated with extracting EGF from human or animal tissues.
- Primary Mechanism of Action
rhEGF does not directly kill bacteria or provide nutrients, but acts as a signaling molecule by binding to specific receptors on the cell surface, initiating a series of intracellular signaling cascades, thereby:
Promote cell proliferation: Stimulate the division and proliferation of epithelial cells, fibroblasts, and other cells.
Promote cell migration: Guide surrounding healthy cells to move toward the wound area and cover the injury.
Promote angiogenesis: Improve microcirculation at the wound site, providing oxygen and nutrients for tissue repair.
Regulating extracellular matrix synthesis: promoting the production of substances such as collagen, improving healing quality, and reducing scar formation.
- Key Application Areas
Skincare (as a cosmetic ingredient)
This is a highly popular direction in recent years, primarily claimed to have effects such as “repair,” “anti-aging,” and “skin renewal.”.
Repair the skin barrier: Specifically designed for sensitive skin and post-procedure skin after medical treatments such as laser or microneedling, it helps restore the compromised skin barrier.
Anti-wrinkle and anti-aging: By stimulating collagen production and increasing skin thickness, it helps improve fine lines and wrinkles.
Fade acne marks: Accelerate epidermal renewal and aid in the metabolism of acne marks (hyperpigmentation).
It’s still can be used in Pharmaceutical field for trauma Repair
Recombinant Human Epidermal Growth Factor (EGF) Packaging and Shipping:
Packaging: 10g/bag, 100g/ bag, 1kg/bag or as customer’s required.
Shipping : DHL/ FedEx/ Air shipping
Recombinant Human Epidermal Growth Factor (EGF) Storage:
It should be sealed and stored in 2-8℃, well ventilated place, away from incompatible substances (such as strong oxidants).
