(R)-MonoPhos

Product Name: (R)-MonoPhos

CAS No.: 157488-65-8

Chemical Structure:

(R)-MonoPhos Application:

(R)-MonoPhos is a chiral monodentate phosphoramidite ligand widely used in asymmetric catalysis. Featuring a phosphite–amine structure derived from chiral BINOL or related frameworks, it provides excellent control over enantioselectivity in various transition-metal-catalyzed reactions. Due to its unique steric and electronic characteristics, (R)-MonoPhos has become an indispensable tool in fine chemical synthesis, pharmaceuticals, and advanced materials research, particularly where high enantiomeric purity is required. Applications:

1. Asymmetric Hydrogenation Catalyst:
   (R)-MonoPhos is commonly used as a ligand in asymmetric hydrogenation reactions catalyzed by transition metals such as rhodium and ruthenium. It provides high enantioselectivity, making it ideal for the production of optically active alcohols, amines, and carboxylic acid derivatives in pharmaceutical and agrochemical synthesis.

2. Enantioselective Cross-Coupling Reactions:
   This ligand enhances selectivity and reactivity in metal-catalyzed cross-coupling processes, including Suzuki–Miyaura and Heck reactions. Its chiral environment influences product configuration, facilitating the synthesis of complex chiral molecules used in fine chemicals and materials science.

3. Pharmaceutical and Fine Chemical Research:
   Owing to its ability to deliver high enantioselectivity, (R)-MonoPhos is widely utilized in medicinal chemistry and industrial R&D for developing chiral intermediates and APIs. It plays a key role in constructing stereochemically defined compounds that meet strict regulatory standards in drug manufacturing.

(R)-MonoPhos Packaging and Shipping:

Packaging: 1g/ bag, 10g/ bag, 1kg/bag or as customer’s required.

Shipping : DHL/ FedEx/ Air shipping

(R)-MonoPhos Storage:

Store in Dry and Ventilated place with the Room Temperature, Preserved in Original Tight-Closed containers, Keep Away from Light and Heating.