N-(p-Toluenesulfonyl)-3-pyrroline

Product Name: N-(p-Toluenesulfonyl)-3-pyrroline

Other Name: 1-(4-methylphenyl)sulfonyl-2,5-dihydropyrrole; N-TOSYL-3-PYRROLINE; 1-tosyl-2,5-dihydro-1H-pyrrole

CAS No.: 16851-72-2

Chemical Structure:

N-(p-Toluenesulfonyl)-3-pyrroline Application:

N-(p-Toluenesulfonyl)-3-pyrroline is an organic compound belonging to the class of sulfonamide derivatives, widely recognized for its value as a versatile intermediate in synthetic organic chemistry. It combines the reactivity of a pyrroline ring with the stability and directing properties of a p-toluenesulfonyl (Ts) group, making it a key building block in the preparation of nitrogen-containing heterocycles, pharmaceuticals, and fine chemicals. With its balanced solubility and strong electron-withdrawing capacity, this compound facilitates a range of selective chemical transformations under mild conditions. It is commonly used in laboratory-scale synthesis as well as industrial R&D settings, especially in medicinal and catalytic chemistry. Applications:

1. Pharmaceutical Intermediate:
   N-(p-Toluenesulfonyl)-3-pyrroline serves as an important intermediate for synthesizing nitrogen-containing drug molecules. Its pyrroline core structure provides a flexible framework for the construction of pyrrolidine derivatives, which are frequently found in bioactive compounds, enzyme inhibitors, and CNS-related drugs.

2. Organic Synthesis Building Block:
   In organic synthesis, this compound is used as a key precursor for functional group transformations, such as oxidation, reduction, or substitution reactions. The toluenesulfonyl group acts as a protective and activating moiety, allowing chemists to selectively modify the pyrroline ring while maintaining structural integrity.

3. Catalysis and Material Research:
   N-(p-Toluenesulfonyl)-3-pyrroline is also employed in the development of chiral catalysts and fine chemicals. Its stable sulfonamide linkage provides a rigid structural element useful for ligand design in asymmetric catalysis and for synthesizing specialty polymers or advanced materials.

N-(p-Toluenesulfonyl)-3-pyrroline Packaging and Shipping:

Packaging: 10g/bag, 100g/ bag, 1kg/bag or as customer’s required.

Shipping : DHL/ FedEx/ Air shipping

N-(p-Toluenesulfonyl)-3-pyrroline Storage:

Store in Dry and Ventilated place with the Room Temperature, Preserved in Original Tight-Closed containers, Keep Away from Light and Heating.