Product Name: Hoveyda-Grubbs 2nd
Other Name: (1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM; HOVEYDA-GRUBBS CATALYST; Hoveyda-Grubbs Catalyst 2nd Generation; Hoveyda-Grubbs Catalyst 2nd;
CAS No.: 301224-40-8
Chemical Structure:
Hoveyda-Grubbs 2nd Application:
Hoveyda–Grubbs 2nd Generation Catalyst is a well-established ruthenium-based metathesis catalyst widely applied in academic research and industrial synthesis. Compared with first-generation systems, this catalyst offers improved initiation rates, greater thermal stability, and enhanced tolerance to diverse functional groups. Its unique structural modification, featuring a chelating isopropoxybenzylidene ligand, makes it more robust under reaction conditions, delivering reliable performance in demanding processes.
Olefin metathesis is one of the most versatile and efficient transformations in modern synthetic chemistry. By enabling the selective formation and cleavage of carbon–carbon double bonds, the Hoveyda–Grubbs 2nd Generation Catalyst allows chemists to build complex molecules with high atom economy. It has become indispensable for pharmaceutical intermediates, specialty chemicals, and materials science, where precision and reproducibility are crucial. Applications:
Pharmaceutical and Fine Chemicals
The catalyst is a powerful tool in drug discovery and active pharmaceutical ingredient (API) development. It enables the efficient assembly of heterocycles, macrocycles, and natural product analogs, where selective olefin metathesis is required. Its stability and compatibility with sensitive functional groups make it a preferred choice for fine chemical synthesis at both research and pilot scales.Polymer and Advanced Materials
In materials science, Hoveyda–Grubbs 2nd Generation Catalyst plays a central role in ring-opening metathesis polymerization (ROMP) and the synthesis of advanced polymeric structures. It allows researchers and manufacturers to design specialty polymers with defined architectures, enhanced mechanical strength, and tailored physical properties, supporting innovation in coatings, electronics, and high-performance composites.Research and Academic Development
This catalyst is widely adopted in universities and R&D institutions for mechanistic studies, methodology development, and the exploration of new catalytic processes. Its well-documented reactivity profile provides a reliable foundation for innovative research, while its reproducibility ensures consistency across experiments.
Hoveyda-Grubbs 2nd Packaging and Shipping:
Packaging: 10g/bag, 100g/ bag, 1kg/bag or as customer’s required.
Shipping : DHL/ FedEx/ Air shipping
Hoveyda-Grubbs 2nd Storage:
Please store in a well ventilated, dry place at 2-8 ℃ and avoid direct sunlight.
