Grubbs Catalyst, 3nd Generation

Product Name: Grubbs Catalyst, 3nd Generation

Other Name:  Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](benzylidene)bis(3-bromopyridine)ruthenium(II)

CAS No.: 900169-53-1

Chemical Structure:

Grubbs Catalyst, 3nd Generation Application:

Grubbs Catalyst, 3nd Generation, is a ruthenium-based metathesis catalyst featuring a fast-initiating N-heterocyclic carbene (NHC) ligand and a pyridine group that improves reactivity and stability. It represents an evolution of the previous Grubbs and Hoveyda–Grubbs generations, offering higher activity, broader substrate compatibility, and tolerance to air and moisture. This catalyst is widely used in advanced organic synthesis, polymer chemistry, and fine chemical manufacturing. Its robustness and efficiency make it a preferred reagent for industrial-scale olefin metathesis and R&D in complex molecular design. Applications:

1. Olefin Metathesis Reactions
   Grubbs Catalyst, 3nd Generation exhibits excellent efficiency in ring-closing metathesis (RCM), ring-opening metathesis (ROM), and cross-metathesis (CM). It enables precise control over molecular architecture and double-bond formation, making it indispensable in synthesizing functionalized alkenes, natural product analogs, and macrocycles under mild conditions.

2. Polymer and Material Synthesis
   The catalyst is ideal for ring-opening metathesis polymerization (ROMP) and other precision polymerizations. Its high functional-group tolerance allows the formation of advanced polymeric materials with well-defined molecular weights and architectures, contributing to innovations in materials science, coatings, and biocompatible polymers.

3. Pharmaceutical and Fine Chemical Development
   Owing to its remarkable stability and catalytic efficiency, Grubbs Catalyst, 3nd Generation is widely used in the synthesis of drug intermediates, complex molecular scaffolds, and bioactive compounds. It supports large-scale, cost-effective processes with reduced waste and improved yield, aligning with green chemistry principles.

Grubbs Catalyst, 3nd Generation Packaging and Shipping:

Packaging: 1g/ bag, 100g/ bag, 1kg/bag or as customer’s required.

Shipping : DHL/ FedEx/ Air shipping

Grubbs Catalyst, 3nd Generation Storage:

Please store in a well ventilated, dry place at 2-8 ℃ and avoid direct sunlight.