Product Name: Grela 2nd Generation
Other Name: [1,3-bis (2,4,6-trimethylphenyl) -2- imidazolidinylidene] (2-isopropoxy-5-nitrophenyl methylene) ruthenium dichloride; nitro-Grela; Grela nitro-Grela; Grela’s catalyst; Grela 2
CAS No.: 502964-52-5
Chemical Structure:

Grela 2nd Generation Application:
Grela 2nd Generation Catalyst is an advanced ruthenium-based olefin metathesis catalyst designed for high-performance reactions in organic and polymer synthesis. This catalyst features an optimized N-heterocyclic carbene (NHC) ligand architecture and a chelating benzylidene moiety, offering excellent activity, selectivity, and stability under a wide range of conditions. Its robust design enables efficient catalysis even in the presence of functional groups or polar solvents, making it ideal for both academic research and industrial-scale synthesis.
With exceptional performance in ring-closing metathesis (RCM), cross-metathesis (CM), and ring-opening metathesis polymerization (ROMP), the Grela 2nd Generation Catalyst offers a balance of reactivity and tolerance. Compared with traditional Grubbs or Hoveyda catalysts, it delivers faster initiation rates and superior productivity. Its broad compatibility with diverse substrates makes it widely adopted in the synthesis of fine chemicals, pharmaceuticals, and specialty polymers. Applications:
Ring-Closing Metathesis (RCM) – Applied in the synthesis of cyclic compounds, natural product analogs, and complex heterocycles with high efficiency and selectivity.
Cross-Metathesis (CM) – Used for constructing C=C bonds between different olefins, enabling advanced molecular modification and functional material design.
Ring-Opening Metathesis Polymerization (ROMP) – Serves as a key catalyst in preparing specialty polymers and advanced materials with controlled architectures and molecular weights.
Grela 2nd Generation Packaging and Shipping:
Packaging: 1g/ bag, 10g/ bag, 1kg/bag or as customer’s required.
Shipping : DHL/ FedEx/ Air shipping
Grela 2nd Generation Storage:
Please store in a well ventilated, dry place at 2-8 ℃ and avoid direct sunlight.

