Product Name: Glutamylamidoethyl Imidazole
Other Name: Pentanoic acid, 4-amino-5-[[2-(1H-imidazol-4-yl)ethyl]amino]-5-oxo-, (4S)-
CAS No.: 169283-81-2
Chemical Structure:

Glutamylamidoethyl Imidazole Application:
Glutamylamidoethyl Imidazole is a synthetic organic compound featuring both an imidazole ring and a glutamylamide moiety, offering unique reactivity and biocompatibility. It is widely used as an intermediate in biochemical synthesis, peptide modification, and pharmaceutical research. The molecule’s dual functional groups — an imidazole capable of proton exchange and a glutamyl derivative with strong hydrogen bonding potential — make it particularly valuable in designing biologically relevant compounds.
In biochemical and pharmaceutical applications, Glutamylamidoethyl Imidazole serves as a key building block for enzyme inhibitors, peptide conjugates, and histidine analogs. Its structure mimics natural amino acid motifs, allowing it to participate in catalytic reactions and molecular recognition studies. Researchers employ it in structure–activity relationship (SAR) investigations, drug metabolism modeling, and enzymatic reaction simulations due to its compatibility with various peptide and protein systems.
The compound also finds use in biotechnology as a linker or spacer in enzyme immobilization and biofunctionalized materials. Its imidazole ring facilitates controlled binding to metal ions and catalytic sites, making it suitable for affinity chromatography media, biosensor construction, and biocatalytic platform design.
In addition, Glutamylamidoethyl Imidazole can act as a precursor in custom synthesis of functionalized peptides, helping to improve solubility, molecular stability, and receptor selectivity. The compound’s stability under physiological conditions and ease of derivatization make it an attractive choice for R&D environments focused on medicinal chemistry, peptide science, and advanced materials engineering.
Overall, Glutamylamidoethyl Imidazole is a versatile specialty chemical that bridges organic synthesis and bioengineering, offering chemists and researchers a reliable intermediate for designing next-generation functional biomolecules. Applications:
Pharmaceutical and Biochemical Intermediate
Used in the synthesis of enzyme inhibitors, peptide analogs, and bioactive compounds for drug discovery and molecular biology research.Bioconjugation and Enzyme Immobilization
Serves as a functional linker due to its imidazole moiety, enhancing enzyme stability and affinity in immobilized biocatalyst systems.Analytical and Catalytic Research
Applied in metal-binding studies, affinity chromatography, and catalytic mechanism investigations involving histidine-like structures.
Glutamylamidoethyl Imidazole Packaging and Shipping:
Packaging: 10g/bag, 100g/ bag, 1kg/bag or as customer’s required.
Shipping : DHL/ FedEx/ Air shipping
Glutamylamidoethyl Imidazole Storage:
Store in Dry and Ventilated place with the Room Temperature, Preserved in Original Tight-Closed containers, Keep Away from Light and Heating.

