5-Amino-1-Methylquinolinium Iodide（NNMTi）

Product Name: 5-Amino-1-Methylquinolinium Iodide

Other Name: 5-amino-1MQ; NNMTi; 5-Amino-1methylquinolinium iodide; 5-Amino-1-methylquinolinium; NNMTi 5-amino-1MQ;

CAS No.: 42464-96-0

Chemical Structure:

5-Amino-1-Methylquinolinium Iodide Application:

5-Amino-1-Methylquinolinium Iodide (commonly called 5‑Amino‑1MQ) is a synthetic quinolinium salt and a selective, substrate-site targeting inhibitor of nicotinamide N‑methyltransferase (NNMT) . Main Applications:

1. NNMT Inhibition in Biochemical Research
    Serves as a selective NNMT inhibitor, effectively reducing nicotinamide N‑methylation in biochemical assays.

2. Metabolic and Obesity Studies
    Under investigation in animal models for reducing adipogenesis, improving lipid metabolism, and supporting weight management through enhanced NAD⁺ and SIRT1 activity

3. Muscle Regeneration & Aging Research
    Demonstrated to activate aged muscle stem cells (muSCs), promote myoblast differentiation, and enhance skeletal muscle regeneration post-injury.

4. Cell-Based Assays & Screening
    Suitable for high-throughput screening of NNMT-related pathways, metabolic enzyme panels, and pathway modulators in pharmacological research.

5. Pharmaceutical R&D Tool
    Used in early-stage drug discovery targeting metabolic disorders, age-related muscle decline, and energy homeostasis.

5-Amino-1-Methylquinolinium Iodide Packaging and Shipping:

Packaging: 1kg/ bag, 25kg/ drum or as customer’s required.

Shipping : DHL/ FedEx/ Air shipping/ Ocean shipping

5-Amino-1-Methylquinolinium Iodide Storage:

Store in Dry and Ventilated place with the Room Temperature, Preserved in Original Tight-Closed containers, Keep Away from Light and Heating.