Natural Micron Pharm Tech


Creatine Monohydrate: Definition, Preparation, Benefits, Side Effects

Creatine monohydrate is used as a pharmaceutical raw material and health product additive. It has a high reputation all over the world. So do you know how creatine monohydrate is made? What is its specific use? What are its benefits, and side effects and how is it different from creatine? In this article, Natural Micron will answer these questions in detail, hoping to give you a better understanding of creatine monohydrate.

Now, let’s get started!

What is creatine monohydrate?

Creatine monohydrate is a specialized form of creatine, a naturally occurring compound. Mainly used in pharmaceutical raw materials and health care product additives. Creatine monohydrate is one of the healthiest supplements available and is particularly suitable for use as a dietary supplement. Creatine monohydrate is relatively stable and safe, and is easily absorbed by the body. Taking creatine regularly can help replenish your body’s creatine reserves.

In addition to its performance-enhancing properties, creatine monohydrate also has positive effects in the treatment of certain conditions, including neurological disorders and muscle-related disorders.

How is creatine monohydrate made?

Creatine monohydrate is mainly divided into two methods: chemical synthesis and natural extraction. The following is an overview of the methods for preparing creatine monohydrate through these two methods.

Chemical synthesis

The main starting materials for chemical synthesis are sarcosine (a derivative of glycine) and cyanamide.

Sarcosine and cyanamide react together in the presence of specific catalysts and solvents.

This reaction leads to the formation of creatine, which can be further crystallized to obtain creatine monohydrate.

The resulting creatine crystals are then purified, usually through a filtration and drying process.

Natural extraction

Creatine is found naturally in foods such as red meat and fish. Creatine monohydrate is also found in small amounts in some dairy products and nuts.

Grind natural sources such as meat into a fine powder.

The powder is then mixed with water or other solvents to form a slurry.

The slurry is filtered to remove impurities, leaving a creatine-rich liquid.

The liquid is then further processed to extract the creatine crystals.

Creatine is usually obtained in crystalline form in both chemical synthesis and natural extraction methods. These crystals can be further purified and processed to produce creatine monohydrate.

What is creatine monohydrate used for?

Creatine monohydrate is widely used and has many uses besides being a supplement.

  • It is used to manufacture nutritional supplements and nutritional fortifiers that promote the adaptation of skeletal muscles to strenuous exercise and combat fatigue in weak individuals.
  • Preparation of medicines for the treatment of heart disease and respiratory insufficiency.
  • It is used to compound a new healthy food, which has the effect of anti-aging and restoring physical strength.
  • Preparation of pharmaceutical preparations containing human growth hormone.
  • Food additives, cosmetic surfactants, feed additives, beverage additives, pharmaceutical raw materials, and healthcare product additives can also be directly made into capsules and tablets for oral administration.
  • It is usually used as an additive for food, feed, and beverages, and is also used as a raw material for nutritional and healthcare products.

What are the benefits of creatine monohydrate?

Creatine monohydrate is a widely used dietary supplement that has numerous benefits. Let’s take a look at the main benefits of creatine hydrate.

  • Quickly restore physical fitness, accelerate human protein synthesis, enhance muscle elasticity, reduce cholesterol, blood lipids, and blood sugar levels, increase the water content of muscle cells, help muscle cells store energy, increase protein synthesis, etc.
  • Creatine monohydrate is suitable for regular, rhythmic, high-intensity, and explosive exercise.
  • It is suitable for both men and women of all ages. Creatine supplements are not prohibited by any sports and fitness organization.
  • In addition to improving exercise performance (endurance, strength, speed, power), bodybuilders use creatine monohydrate to help speed muscle recovery, promote lean muscle growth, hydrate muscle tissue, and promote nutrient flow.
  • Reduce muscle cell damage and inflammation after strenuous exercise and help the body recover faster.
  • Creatine monohydrate has neuroprotective properties and may improve muscle function in patients with mitochondrial diseases.
  • Creatine monohydrate may improve cognitive function, especially in states that require short-term memory and rapid information processing.
  • Treats a variety of diseases, including muscular dystrophy, ALS (amyotrophic lateral sclerosis), ischemic heart disease, and more.

What are the side effects of creatine monohydrate?

Although creatine monohydrate has many benefits, you should also be aware of its side effects when using it. You may use the potential side effects below for reference.

  • Some people may experience mild stomach upset, nausea, or diarrhea.
  • Creatine causes the muscles to draw water from other parts of the body. This causes the body to become dehydrated.
  • Some people may be allergic to creatine monohydrate or other ingredients in the supplement.
  • Low-purity creatine not only has no obvious effect but is also harmful to the human body. The harmful substance is mainly a derivative called dicyandiamide, which will increase the excretion burden of the kidneys. The dicyandiamide content in 99.99% pure creatine is less than 20PPM.
  • Because creatine can quickly replenish energy. Therefore, it is easy to overtrain during training.
  • Some users may notice slight weight gain due to water retention in muscle cells.

What’s the difference between creatine monohydrate and creatine?

Finally, let’s compare the differences between creatine hydrate and creatine.

Creatine is a naturally occurring compound, and creatine monohydrate is a specialized form of creatine that is made up of creatine molecules bound to water molecules.

Creatine also includes many types including: creatine ethyl ester, creatine hydrochloride, etc. The purity of creatine monohydrate is very high, the creatine content is between 88-90%, and the rest is water molecules, which can be said to be pure creatine.

Creatine monohydrate is widely marketed as a dietary supplement in powder or pill form.

In the end

Creatine monohydrate has many benefits and is loved by many fitness professionals. However, its side effects cannot be underestimated, so you must pay more attention to the changes in your body when using it.

If you need creatine monohydrate or have any questions about it, please contact Natural Micron and our team will respond promptly to your questions.

We also provide free samples for you to test, you can check the page below for detailed information about creatine monohydrate, and contact us now to get the best quote!

Creatine Monohydrate (CAS: 6020-87-7)

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